Clinical-stage gut microbiome therapeutics

Disease-specific microbiome transplants—delivered with clinical precision.

LND Therapeutics develops healthy-donor, full-consortia microbiome transplants using proprietary delivery technology for disease-specific clinical applications.

Full-consortia microbiome

Whole-community donor products designed for clinical use.

Disease-specific programs

Distinct products across oncology, non-malignant, and eating disorders.

12-month shelf life approved Stored at −80 °C 84/84 rCDI cured (WCoID 2023)

Clinical portfolio

LND capsule platform
Clinical-stage

Approved shelf life

12 mo

Storage

−80 °C

rCDI outcome (LND 101)

84 / 84

Product suite

LND 101–103

What is a microbiome transplant?

A microbiome transplant introduces a healthy donor’s full microbial community to help restore ecosystem balance and function. LND’s approach is built around full-consortia products, disease-specific development, and clinical operational readiness.

Disease-specific development

Product strategy is aligned to indication biology (oncology, non-malignant, eating disorders).

Clinical-grade storage

Health Canada approval for a 12-month shelf life with storage at -80°C.

Proprietary delivery technology

A platform designed to deliver donor consortia reliably and consistently.

Evidence-led iteration

Development informed by documented clinical outcomes and ongoing trial programs.

12 mo

Approved shelf life

-80°C

Validated storage

84/84

rCDI cured (LND 101)

3

Clinical-stage products (101–103)

Capsules and analytics

A clinical portfolio across indications, plus analytics to support discovery and monitoring.

LND 101
Oncology

Capsule product focused on cancer patients.

Indications

Melanoma, lung, pancreatic, renal, breast

Stage

Phase 2b / Phase 1 (varies by indication)

LND 102
Non-malignant

Capsule product for a range of non-malignant conditions.

Focus

ALS, Parkinson’s, Fibromyalgia, MASLD

Stage

Phase 1 + Phase 2 planning

LND 103
Low-volume

Concentrated low-volume capsule product for eating disorders.

Indication

Anorexia Nervosa

Stage

Phase 1

Analysis
Multi-omics

End-to-end analytics to support trials and cohorts.

Includes

Metagenomics, functional/EC, metabolites, 16S rRNA

Outputs

Clinician-ready summaries & reproducible reporting

A compliant, repeatable clinical pathway

From donor sourcing to storage and program execution, we support partners with an operational model designed for clinical delivery.

01
Screen & Qualify

Healthy donor screening and qualification aligned to clinical-grade standards.

02
Manufacture

Standardized preparation using proprietary technology for consistent delivery.

03
Store & Supply

Approved 12-month shelf life with storage at -80°C and controlled logistics.

04
Track & Learn

Program monitoring and analytics to link microbiome changes to outcomes.

Selected outcomes and milestones

A rotating view of clinical outcomes, approvals, and portfolio updates.

View all news
World Congress of Infectious Diseases • 2023
LND 101 in recurrent C. difficile: 84/84 cured

Documented 84/84 patients with recurrent C. difficile cured (97.5% one-sided CI of failure rate 0.0–4.3%). (Parvathy S., 2023)

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Regulatory milestone
Health Canada-approved 12-month shelf life

Product storage validated at -80°C with a 12-month shelf life approval to support reliable clinical supply.

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Portfolio update
Three clinical-stage products, indication-specific development

LND 101 targets oncology settings, LND 102 covers multiple non-malignant conditions, and LND 103 is a concentrated low-volume product for eating disorders.

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